This mural is a well-known landmark on North Florida Avenue downtown.
The mural actually faces Royal Street, but the building address is North Florida Avenue. The artist is Carl Cowden III, a graduate of the University of Tampa, and he has painted several murals in the Tampa Bay Area. Click here to read a nice article about Cowden. The mural includes the downtown skyline, a water tower in the north Tampa neighborhood of Sulphur Springs, the Henry Plant Museum on the University of Tampa campus, Gasparilla, the TECO Streetcar in Ybor City, and the area’s natural outdoor beauty.